SINECCH™ for Cosmetic Surgery

SINECCH™ Speeds Facelift, Eyelid Surgery, Rhinoplasty and Breast Augmentation Recovery and Reduces Liposuction Swelling

The dosage regimen of SINECCH™ was custom-designed to match the level of bruising and swelling that many patients experience during the post-operative phase of the most common plastic surgery procedures: facelift recovery , eyelid surgery recovery , rhinoplasty (nose surgery) recovery , breast augmentation recovery, and liposuction (the swelling here can be significant).


Facelift Recovery

SINECCH™'s ability to reduce bruising during facelift recovery has been proven clinically. A 2006 study published in the major plastic surgery journal, the American Medical Association’s Archives of Facial Plastic Surgery, described how SINECCH™ use among facelift patients significantly lessened post-operative bruising.

A computer imaging program was used to objectively determine the amount of bruising and associated skin color changes in 29 patients, all of whom underwent the same surgical facelift procedure performed by the same doctors. Photographs were taken of the patients on post-operative days (PODs) 1, 5, 7, and 10. One group of patients received SINECCH™ according to the SINECCH™ protocol, and the other patients received a placebo (sugar pill) according to the same protocol. The patients didn't know whether they were taking SINECCH™ or the placebo, and neither did the plastic surgeon who assessed the bruising with digital imaging during the facelift recovery period.

Overall, the placebo group had 24 percent more bruising than the SINECCH™ group.

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The Difference in Bruising on PODs 1 and 7 Was Statistically Significant

On POD 1, the placebo group had on average 26 percent more square centimeters (cm) of bruising than the SINECCH™ group. The probability of this result happening by chance (the P-value) was analyzed and found to be less than 0.005 — that is, it was less than 5 chances out of 1,000. It is extremely unlikely that this result was simply by chance. The reduction in bruising was 7 square inches less one day after the surgery among the patients who took SINECCH™.

On POD 7, the results were 41 percent more square cm of bruising in the placebo group (P<0.001, less than 1 chance out of 1,000 that this was due to chance). This amounted to an average of 9 square inches less bruising on the face among the SINECCH™ users a week after the facelift.

Many plastic surgeons in the United States routinely give their patients SINECCH™ to help reduce bruising and swelling during the facelift recovery period — for good reason. Contact Alpine Pharmaceuticals to learn more about the clinically proven benefits of SINECCH™.

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Eyelid Surgery Recovery

The delicate skin, blood vessels, and tissue around the eyes are certainly vulnerable to the trauma of surgery. Blepharoplasty (eyelid surgery) is performed on thousands of people every year, and even many plastic surgeons undergo this surgery. Here's a testimonial from a cosmetic surgeon/professor of plastic surgery who used SINECCH™ for his own eyelid surgery recovery:

Dr. James L. Baker: I have been using SINECCH™ since January 1997, when I had my eyelid surgery performed, and my ophthalmoplastic surgeon from New York utilized SINECCH™ plus bromelain. Since that time we have used this combination on all our facial aesthetic surgery, as well as ultrasound and conventional liposuction patients. The diminution in bruising and swelling has been quite dramatic, and I have recommended this to many of my colleagues.

James L. Baker MD FACS

Certified by the American Board of Plastic Surgery

Clinical Professor of Plastic Surgery University of South Florida

Winter Park, Florida

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Rhinoplasty Recovery

According to the American Society for Aesthetic Plastic Surgery (ASAPS), nose surgery (rhinoplasty) recovery will entail some degree of both bruising and swelling. The ASAPS notes that:

  • Bruising is most apparent during the first three days after surgery, around the eyes and cheeks.
  • Most of the discoloration disappears within a week.
  • Noticeable swelling can last for several weeks.
  • Minor residual swelling, usually affecting the tip of the nose, might continue for many months, but it generally won't be noticeable to other people.

The degree of bruising and swelling that are seen during rhinoplasty recovery can definitely be addressed by using SINECCH™. As is also the case for other types of cosmetic and general surgeries, SINECCH™ can help to reduce or even eliminate the bruising and swelling in the post-operative rhinoplasty recovery phase. A recent patient in Hawaii asked her surgeon on the sixth day after her rhinoplasty surgery, “When does the bruising start?” This level of response will not happen for every patient, but almost every patient will experience a significant reduction in both bruising and swelling.

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Breast Augmentation Recovery

Breast augmentation is more popular than ever among women who'd like to enhance what nature gave them or restore what disease has taken away. The American Society of Plastic Surgeons (ASPS) notes that nearly 255,000 breast enhancement implant surgeries were performed in 2003, nearly twice the number done in 1998. This figure doesn't include the 68,000 women who had breast implants for reconstruction following a mastectomy due to cancer or other disease.

The breast augmentation recovery period does involve some bruising and swelling. The website of the ASAPS states that discoloration and swelling occur initially after the breast implant procedure, and then resolve over days or weeks; most of the lasting swelling recedes within a month.

Many plastic surgeons have their patients use SINECCH™ in the breast augmentation recovery phase to combat the swelling and bruising by the surgery. If you are considering breast augmentation (or reduction) surgery, contact Alpine Pharmaceuticals to find out more about the benefits of SINECCH™.

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Liposuction Swelling and Bruising

Liposuction is now the third most popular cosmetic procedure, with almost 204,000 surgeries performed in 2010, according to the American Society of Plastic Surgery. A surgeon removes fat from certain areas of the body (e.g., thighs, abdomen, buttocks, face) by liquefying it and suctioning it out through a narrow tube or needle. After liposuction, swelling and bruising are a common occurrence, since the procedure does cause the body significant trauma. SINECCH™ was clinically proven to reduce post-operative liposuction swelling and bruising in a 2002 study.

In that study, liposuction surgeries in 29 female patients aged 18–45 were performed by the same surgeon. All of the patients had liposuction of the central areas of the body: the abdomen, buttocks, or thighs. The amount of fat removed from each patient was measured. Similar amounts of fat were taken from the patients in both the SINECCH™ and placebo groups. Photographs were then taken of the patients from the front, rear, left, and right sides at post-operative weeks 1, 2, 3, and 4. Independent plastic surgeons with experience in liposuction were then asked to rank the 29 patients’ photo sets from most to least bruising and swelling at each post-op week.

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SINECCH™ Use Significantly Reduced Liposuction Swelling and Bruising

The probability (P)-values for three independent plastic surgeons were P<0.006, P<0.003, and P<0 .0001 in favor of SINECCH™ reducing liposuction bruising and liposuction swelling. This means that the SINECCH™ patients had dramatically less bruising and swelling than the placebo group patients. In fact, almost all of the patients who took the placebo had more bruising than any of the SINECCH™ patients. The surgeon who performed all the liposuction surgeries reported that he was astonished to see that three patients, all in the SINECCH™ group, had no bruising or swelling seven days after the surgery when they returned for their first follow-up visit and were photographed. The surgeon had been in practice for many years and had never seen or heard of such rapid smooth recoveries from liposuction.

This study was presented at the annual meeting or the American Society of Aesthetic Plastic Surgery in April 2002.

A Testimonial:

I have noted a marked decrease in post-operative swelling and bruising in patients who have taken SINECCH™. The results are present with all procedures including facial surgery, liposuction, and breast surgery. Patients have been pleased, and no adverse effects have been seen.

Scott C. Sessions MD FACS

Certified by the American Board of Plastic Surgery

The beneficial effects of SINECCH™ for cosmetic surgery procedures have been experienced by thousands of patients. Explore the clinical benefits of SINECCH™ for your post-operative recovery. Contact Alpine Pharmaceuticals, or you can order SINECCH™ now.

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